מקורות מידע מומלצים על תזונה קטוגנית

אפרט כאן מספר בלוגים, אנשים, קבוצות, סרטונים וספרים שמכילים המון מידע מעולה על תזונה קטוגנית.

לPeter Attia רופא במקצועו יש בלוג מעולה על תזונה באופן כללי וגם על תזונה קטוגנית: eating academy.
הרצאה טובה שלו על כולסטרול:

הרצאה על תזונה ובריאות:

Jeff Volek חוקר בתחום הספורט ותזונה דלת פחמימות עם הרצאה מעולה על יתרונות הקטוזיס:

Jason Fung חוקר ורופא בתחום הסכרת עם הרצאות מעולות ובלוג: intensive dietary management.
סקירה שאני מעביר על הספר שלו The Obesity Code: Unlocking the Secrets of Weight Loss

Dominic D’Agostino רופא וחוקר סרטן בתחום התזונה הקטוגנית:

Ron Rosedale רופא שעוסק שנים רבית בתחום התזונה הקטוגנית ואריכות חיים בעל ספר והרצאות מעולות:

Ivor Cummins מהנדס במקצועו וחוקר נלהב של תזונה עם הרצאות מרתקות בתחום. בנוסף יש לו דף פייסבוק פעיל עם המון מידע מעניין: TheFatEmperor. הבלוג שלו: The Fat Emperor.

 

 

Nora Gedgaudas בעלת בלוג וספר מעולים בתחום התזונה דלת הפחמימות. הבלוג: primalbody-primalmind.
הספר שלה נקרא Primal Body, Primal Mind: Beyond the Paleo Diet for Total Health and A Longer Life.

Gary Taubes כתב מדעי בתחום התזונה בעל ספר ובלוג מעולים. הבלוג: Gary Taubes.
הספר רב המכר שלו: Good Calories, Bad Calories
הרצאה:

Richard David Feinman פרופסור לביוכימיה עם ספר מעולה שהעברתי עליו כאן ביקורת: The World Turned Upside Down: The Second Low-Carbohydrate Revolution.

Dr. Stephen Phinney

 

הרצאה של Marty Kendall על חשיבות איכות המזון שצורכים. בנוסף יש פוסט בנפרד על ההרצאה הזאת כשמהנדסים פוגשים את מדעי התזונה.

הרצאה על תנגודת אינסולין

הרצאה על חלבון, אינסולין וגלוקגון

Dr Michael Eades

בלוגים נוספים מומלצים:

הבלוג של L Amber O’Hearn בלוגרית חומר מעולה. The Ketogenic Diet for Health.
 הרבה מאמרים מעולים תזונה. carbsanity.
 הבלוג של אביב מייזלין על תזונה קטוגנית. מעבר לפליאו
 מאמרים מתורגמים לעברית של הרבה מומחים בתחום. בריאות בעברית
בלוג שמוקדש לאפס פחמימות. zerocarbzen.
בלוג גדול על תזונה קטוגנית, תזונה נמוכה בפחמימות וכול מה שקשור. buttermakesyourpantsfalloff
בלוג טכני ומעמיק על ביוכימיה ותזונה קטוגנית. HYPERLIPID.
הבלוג של Jason Fung, intensive dietary management.
הבלוג של Peter Attia, eating academy.
הבלוג של Ivor Cummins, The Fat Emperor.
הבלוג שלRichard David Feinman, RICHARD DAVID FEINMAN. Richard Feinman, the Other
הבלוג של Gary Taubes, הרבה לא התעדכן אבל יש הרבה חומר טוב Gary Taubes.
בלוג מקצועי וטכני של George Henderson. The High-fat Hep C Diet.
הבלוג של Dominic D’Agostino. חוקר סרטן עם תזונה קטוגנית. keto nutrition.
הבלוג של Denise Minger, מחברת הביקורת על מחקר סין. deniseminger.
Tuit Nutrition, בלוג על תזונה ותזונה קטוגנית בפרט. tuit nutrition.
הבלוג של Marty Kendall, בלוג על תזונה באופן כללי optimising nutrition.
הבלוג של Petro Dobromylskyj. ביוכימיה, פיזיולוגיה, מחקרים והרבה תיאוריה. HYPERLIPID
בלוג על תזונה קטוגנית breaknutrition
בלוג של Dr. Ede על תזונה diagnosisdiet
הבלוג של Chris Masterjohn על תזונה ופיזילוגיה, הרבה רקע תיאורטי בביוכימיה. chrismasterjohnphd.
BurnFatNotSugar
Yelling Stop
Fat Fueled Family
Just Meat

קבוצות דיון:

מדע דל פחמימה – הקבוצה שלי בפייסבוק.
תזונה קטוגנית
תזונה קטוגנית וספורט
אפס פחמימות
Lower Insulin
reddit
ketogenicforums
העקרון הקרניבורי

הלינקים מהמועדפים שלי (עדכון אחרון 16.02.19)

insulin

Fructose causes insulin resistance

The Deadly Effects of Fructose
What are the minimum and maximum Blood insulin concentrations in the following conditions? – ResearchGate
Insulin: Reference Range, Interpretation, Collection and Panels
Insulin NationBeyond BMI and A1c: Measuring Insulin Resistance – Insulin Nation
Prehepatic Insulin Production in Man: Kinetic Analysis Using Peripheral Connecting Peptide Behavior: The Journal of Clinical Endocrinology & Metabolism: Vol 51, No 3
How to Reverse Diabetes Naturally
Think skinny people don’t get type 2 diabetes? Think again.
A mathematical model of metabolic insulin signaling pathways | Endocrinology and Metabolism
Tissue–Specific Insulin Signaling, Metabolic Syndrome, and Cardiovascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology
Insulin Receptor Signaling in Normal and Insulin-Resistant States

internal fat

Are you a Tofi? (That’s thin on the outside, fat inside) | Science | The Guardian

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men
Effects of pioglitazone on visceral fat metabolic activity in impaired glucose tolerance or type 2 diabetes mellitus. – PubMed – NCBI
Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial. – PubMed – NCBI
Insulin sensitivity and secretion in youth onset type 2 diabetes with and without visceral adiposity. – PubMed – NCBI
Visceral fat resection in humans: effect on insulin sensitivity, beta-cell function, adipokines, and inflammatory markers. – PubMed – NCBI
Visceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study. – PubMed – NCBI
Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease. – PubMed – NCBI
Prevalence and determinants of fatty liver in normal-weight and overweight young adults. The Cardiovascular Risk in Young Finns Study. – PubMed – NCBI
Comparative clinical study between the effect of fenofibrate alone and its combination with pentoxifylline on biochemical parameters and liver stif… – PubMed – NCBI
Insulin resistance index (HOMA-IR) in the differentiation of patients with non-alcoholic fatty liver disease and healthy individuals
The Turkish Journal of Gastroenterology
2014; 25 (Suppl.-1)- 63-8-yeni.pdf

קטוגני כללי

Jeff Volek: The Many Facets of Keto-Adaptation: Health, Performance, and Beyond – YouTube

Dr. Dominic D’Agostino: Metabolic Therapies: Therapeutic Implications and Practical Application – YouTube
Jeff Volek, PhD, RD: How your blood panel values respond to a ketogenic diet – YouTube
The Effects of a Year in Ketosis by James McCarter on Vimeo
7 Lingering Myths Everyone Should Know About Low-Carb Ketogenic Diets « Jimmy Moore’s Livin’ La Vida Low Carb Blog
The Ketogenic Diet for Health: The Ketogenic Diet’s Effect on Cortisol Metabolism
the most ketogenic diet foods | optimising nutrition, managing insulin
Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes – Laffel – 2000 – Diabetes/Metabolism Research and Reviews – Wiley Online Library
Jeff Volek – The Many Facets of Keto-Adaptation: Health, Performance, and Beyond – YouTube
AHS12 Ron Rosedale MD —The Deeper Roots of Health and Diet as Told by Our Ancestor’s Ancestors – YouTube
The Ketogenic Diet for Health: If You Eat Excess Protein, Does It Turn Into Excess Glucose?
The Ketogenic Diet for Health: Protein, Gluconeogenesis, and Blood Sugar
Diabetic, alcoholic and starvation ketoacidosis – Deranged Physiology
Tim Noakes: Full Episode. – YouTube
A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia
Regulation of in vivo ketogenesis: role of free fatty acids and control by epinephrine, thyroid… – Abstract – Europe PMC
Plasma Acetone Metabolism in the Fasting Human
AHS16 – L. Amber O’Hearn – Optimal Weaning – YouTube
Mood and Memory: How Sugar Affects Brain Chemistry- Georgia Ede, MD – YouTube
Загрузка статьи
Marty Kendall — Profile | Tableau Public
Jacob Wilson, PhD — Human Optimization: The Role of Ketogenic Dieting and Resistance Training – YouTube
Systemic, Cerebral and Skeletal Muscle Ketone Body and Energy Metabolism During Acute Hyper-D-β-Hydroxybutyratemia in Post-Absorptive Healthy Males: The Journal of Clinical Endocrinology & Metabolism: Vol 100, No 2
Comparison of Low Fat and Low Carbohydrate Diets on Circulating Fatty Acid Composition and Markers of Inflammation
Hyperlipid: Protons (38) and ultra low fat once more
Vitamin D Deficiency and Type 1 Diabetes
Ketone bodies as a fuel for the brain during starvation
Nutrition and Physical Degeneration: A Comparison of Primitive and Modern Diets and Their Effects | JAMA | The JAMA Network
Dr. Stephen Phinney – ‘Recent Developments in LCHF and Nutritional Ketosis’ (Part 2) – YouTube
Mechanism By Which Dietary Fat Can Raise Blood Glucose And Insulin | Fanatic Cook
JMIR-An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial | Saslow | Journal of Medical Internet Rese
Ketogenic diet – a connection between mitochondria and diet – DoctorMyhill
Effect of a Low-Carbohydrate Diet on Appetite, Blood Glucose Levels, and Insulin Resistance in Obese Patients with Type 2 Diabetes
The ketogenic diet increases mitochondrial glutathione levels – Jarrett – 2008 – Journal of Neurochemistry – Wiley Online Library
Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome
Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: a randomized controlled trial. – PubMed – NCBI
Systemic, Cerebral and Skeletal Muscle Ketone Body and Energy Metabolism During Acute Hyper-D-β-Hydroxybutyratemia in Post-Absorptive Healthy Males | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Ketoacidosis associated with low-carbohydrate diet in a non-diabetic lactating woman: a case report | Journal of Medical Case Reports | Full Text
Induced and controlled dietary ketosis as a regulator of obesity and metabolic syndrome pathologies – ScienceDirect
Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss
Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species
Ketogenic Diet in Neuromuscular and Neurodegenerative Diseases
Keto-Adaptation – Blog | Virta Health
Modulation of oxidative stress and mitochondrial function by the ketogenic diet
Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum
A Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women: The Journal of Clinical Endocrinology & Metabolism: Vol 88, No 4
Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study | SpringerLink
Resting metabolic rate of obese patients under very low calorie ketogenic diet | Nutrition & Metabolism | Full Text
Therapeutic protocol of Paleomedicina Hungary (PDF Download Available)
Is the acetone:glucose ratio the Holy Grail of tracking optimal ketosis? | optimising nutrition
Insulin resistance and outcome in bipolar disorder. – PubMed – NCBI
The Current Status of the Ketogenic Diet in Psychiatry
Is the acetone:glucose ratio the Holy Grail of tracking optimal ketosis? | optimising nutrition
Low-Fat Versus Low-Carbohydrate Weight Reduction Diets
Evidence that supports the prescription of low-carbohydrate high-fat diets: a narrative review | British Journal of Sports Medicine
I Stopped Eating Vegetables for Over 60 Days And Ate A Carnivore Diet! – Kristen Suzanne’s
Low-Fat Versus Low-Carbohydrate Weight Reduction Diets
Evidence that supports the prescription of low-carbohydrate high-fat diets: a narrative review | British Journal of Sports Medicine
I Stopped Eating Vegetables for Over 60 Days And Ate A Carnivore Diet! – Kristen Suzanne’s
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans: Cell Metabolism
How Much Protein Do You Need In Nutritional Ketosis? – Blog | Virta Health
Ketosis, ketogenic diet and food intake control: a complex relationship
Ketone bodies as epigenetic modifiers : Current Opinion in Clinical Nutrition & Metabolic Care
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans: Cell Metabolism
Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome – ScienceDirect
Dom D’Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer (EP.05) – Peter Attia
23 Studies on Low-Carb and Low-Fat Diets — Time to Retire The Fad
Systemic, Cerebral and Skeletal Muscle Ketone Body and Energy Metabolism During Acute Hyper-D-β-Hydroxybutyratemia in Post-Absorptive Healthy Males | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Ketogenic Diets for Psychiatric Disorders: A New 2017 Review | Psychology Today
Short‐term feeding of a ketogenic diet induces more severe hepatic insulin resistance than a obesogenic high‐fat diet – Grandl – – The Journal of Physiology – Wiley Online Library
Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study. – PubMed – NCBI
Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. – PubMed – NCBI
Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome | SpringerLink
Healthy fat cells uncouple obesity from diabetes
The Ten Defining Characteristics of a Well-Formulated Ketogenic Diet – Blog | Virta Health
Low Carb Diet Studies.xlsx – Google Sheets
β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle
Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments – ScienceDirect
Paleo-Ketogenic Diet Benefits (+ Advanced Tips) • Dr Zsofia Clemens PhD
Mechanisms Preserving Insulin Action during High Dietary Fat Intake – ScienceDirect
Influence of medium-chain and long-chain triacylglycerols on the control of food intake in men | The American Journal of Clinical Nutrition | Oxford Academic
Paradox of hypercholesterolaemia in highly trained, keto-adapted athletes | BMJ Open Sport & Exercise Medicine
Alternate Fuel Utilization by Brain
Nutrients | Free Full-Text | Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients
Comparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation. – PubMed – NCBI
Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments. – PubMed – NCBI
Ketone Bodies and Brain Glutamate and GABA Metabolism – Abstract – Developmental Neuroscience 1998, Vol. 20, No. 4-5 – Karger Publishers
Regulation of GABA Level in Rat Brain Synaptosomes: Fluxes Through Enzymes of the GABA Shunt and Effects of Glutamate, Calcium, and Ketone Bodies – Erecińska – 1996 – Journal of Neurochemistry – Wiley Online Library
Dietary fat: From foe to friend? | Science
Change in Food Cravings, Food Preferences, and Appetite During a Low‐Carbohydrate and Low‐Fat Diet – Martin – 2011 – Obesity – Wiley Online Library
Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients | HTML
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis: Cell Metabolism
Adhering to the Ketogenic Diet – Is it Easy or Hard? (Research Review) • Sci-Fit
Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial | The BMJ
Low-carbohydrate diets differing in carbohydrate restriction improve cardiometabolic and anthropometric markers in healthy adults: A randomised clinical trial [PeerJ]

מחלות לב

Lipid levels in patients hospitalized with coronary artery disease: An analysis of 136,905 hospitalizations in Get With The Guidelines – American Heart Journal

Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73) | The BMJ
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease – Progress in Cardiovascular Diseases
Fat Emperor in LC USA Keto Getaway Florida – Insulin Vs Cholesterol – and CAC! – YouTube
Study says there’s no link between cholesterol and heart disease – National Library of Medicine – PubMed Health
Progression of coronary artery calcification seems to be inevitable, but predictable – results of the Heinz Nixdorf Recall (HNR) study. – PubMed – NCBI
What things properly predict Atherosclerosis extent? Have a look ! — The Fat Emperor
The good and the bad in the link between insulin resistance and vascular calcification – Atherosclerosis
The Ratio Between Visceral and Subcutaneous Abdominal Fat Assessed by Computed Tomography Is an Independent Predictor of Mortality and Cardiac Events | Revista Española de Cardiología (English Edition)
Progression of coronary artery calcification seems to be inevitable, but predictable – results of the Heinz Nixdorf Recall (HNR) study
Diversity of Apolipoprotein E genetic polymorphism significance on cardiovascular risk is determined by the presence of Metabolic Syndrome among hypertensive patients
Great News: E4s can avoid CAD by avoiding MetS – ApoE4.Info
apo_e.pdf
An introduction to ApoE4, biochemistry, and possible prevention strategies – ApoE4.Info
Macrophages Facilitate Electrical Conduction in the Heart: Cell
Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease — NEJM
linkinghub.elsevier.com.sci-hub.cc/retrieve/pii/S030372071300244X
The Failing Heart Relies on Ketone Bodies as a Fuel
Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study – The Lancet
Food consumption and the actual statistics of cardiovascular diseases: an epidemiological comparison of 42 European countries | Grasgruber | Food & Nutrition Research
Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA | Heart and Circulatory Physiology
Serious bias in 20 year follow-up study of statin trial | The BMJ
Association between plasma fatty acids and inflammatory markers in patients with and without insulin resistance and in secondary prevention of cardiovascular disease, a cross-sectional study | Nutrition Journal | Full Text
Hyperinsulinemia Predicts Coronary Heart Disease Risk in Healthy Middle-aged Men | Circulation
Association between hemoglobin glycation index with insulin resistance and carotid atherosclerosis in non-diabetic individuals
A Critical Review of the Consensus Statement from the European Atherosclerosis Society Consensus Panel 2017
Hypertriglyceridemic Waist: A Simple Marker of High‐Risk Atherosclerosis Features Associated With Excess Visceral Adiposity/Ectopic Fat | Journal of the American Heart Association
The effect of statins on average survival in randomised trials, an analysis of end point postponement | BMJ Open
Absence of Coronary Artery Calcium Identifies Asymptomatic Diabetic Individuals at Low Near-Term But Not Long-Term Risk of Mortality: A 15-Year Fol… – PubMed – NCBI
Association between HOMA-IR, fasting insulin and fasting glucose with coronary heart disease mortality in nondiabetic men: a 20-year observational study | SpringerLink
Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restri… – PubMed – NCBI
The low-carbohydrate diet and cardiovascular risk factors: Evidence from epidemiologic studies
Impact of Statins on Serial Coronary Calcification During Atheroma Progression and Regression | JACC: Journal of the American College of Cardiology
Diabetes mellitus, blood glucose and the risk of heart failure: a systematic review and meta-analysis of prospective studies – Nutrition, Metabolism and Cardiovascular Diseases
Global Correlates of Cardiovascular Risk: A Comparison of 158 Countries
Ahmed on Twitter: “We suggest dyslipidemia -not LDL- is the predictor of CHD, increased LDL levels is often a component of dyslipidemia, to unmask confounding, other components of dyslipidemia – i.e high TG, low HDL – should be controlled.”
Amelioration of Hyperglycemia with a Sodium-Glucose Cotransporter 2 Inhibitor Prevents Macrophage-Driven Atherosclerosis through Macrophage Foam Cell Formation Suppression in Type 1 and Type 2 Diabetic Mice
LDL-C Does Not Cause Cardiovascular Disease: a comprehensive review of current literature: Expert Review of Clinical Pharmacology: Vol 0, No ja
Association Between Insulin Resistance and Coronary Plaque Vulnerability in Patients With Acute Coronary Syndromes: Insights From Optical Coherence Tomography – Sijing Wu, Wei Liu, Qian Ma, Wei Yu, Yonghe Guo, Yingxin Zhao, Dongmei Shi, Yuyang Liu, Zhiming Zhou, Jianlong Wang, Ruifang Liu, Yujie Zhou, 2018
Dyslipidemia, Coronary Artery Calcium, and Incident Atherosclerotic Cardiovascular Disease: Implications for Statin Therapy from the Multi-Ethnic Study of Atherosclerosis

ספורט

Evidence of muscular adaptations within four weeks of barbell training in women. – PubMed – NCBI

Metabolic characteristics of keto-adapted ultra-endurance runners – Metabolism – Clinical and Experimental
Acute nutritional ketosis: implications for exercise performance and metabolism
Ketogenic diet does not affect strength performance in elite artistic gymnasts | Journal of the International Society of Sports Nutrition | Full Text
Powerlifting Programs | PowerliftingToWin
חלבון בספורט
Short-term Periodization Models: Effects on Strength and Speed-strength Performance
The Effects of Ketogenic Dieting on Body Composition, Streng… : The Journal of Strength & Conditioning Research
Fat-Free Mass Changes During Ketogenic Diets and the Potential Role of Resistance Training. – PubMed – NCBI
10-56-4-LE
Low-Carbohydrate Diets Promote a More Favorable Body Composi… : Strength & Conditioning Journal
Ketogenic Dieting and Body Composition- Beyond the Abstract – Ketogenic.com
Ketogenic diet benefits body composition and well-being but not performance in a pilot case study of New Zealand endurance athletes
The Effects of Ketogenic Dieting on Body Composition, Streng… : The Journal of Strength & Conditioning Research
The Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Males
A Low-Carbohydrate Ketogenic Diet Reduces Body Weight Withou… : The Journal of Strength & Conditioning Research

צומות

long fast

Why do fasting levels not predict hyperinsulinaemia? | Lifestyle Before Medication
#Periscope: What Happened To The So-Called “Muscle Loss” DEXA Scan From My January #Fasting Experiment? #JimmyScopes on Vimeo
Anti-inflammatory mechanism of dieting and fasting revealed — ScienceDaily

כולסטרול

cholesterol chnage

Dr Peter Attia – The Straight Dope on Cholesterol – YouTube
David Diamond- Demonization and Deception in Cholesterol Research – YouTube
The Cholesterol Conundrum – and Root Cause Solution – YouTube
למה הכולסטרול שלי עדיין גבוה, למרות שאני אוכל תזונה דלת פחמימות? פוסט אורח מאת רעות | בלוג דל פחמימות
Is the use of cholesterol in mortality risk algorithms in clinical guidelines valid? Ten years prospective data from the Norwegian HUNT 2 study
A short guide to reverse cholesterol transport | The Science of Human Potential
Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Determine Cardiovascular Risk
High ratio of triglycerides to hdl-cholesterol predicts extensive coronary disease
A/Prof. Ken Sikaris – ‘Making Sense of LDL’ – YouTube
Extreme Nonfasting Remnant Cholesterol vs Extreme LDL Cholesterol as Contributors to Cardiovascular Disease and All-Cause Mortality in 90000 Individuals from the General Population | Clinical Chemistry
A/Prof. Ken Sikaris – ‘Making Sense of LDL’ – YouTube
Extreme Nonfasting Remnant Cholesterol vs Extreme LDL Cholesterol as Contributors to Cardiovascular Disease and All-Cause Mortality in 90000 Individuals from the General Population | Clinical Chemistry
A/Prof. Ken Sikaris – ‘Making Sense of LDL’ – YouTube
Is the LDL response to saturated fat a sign of a healthy individual? | The BMJ
Low Triglycerides–High High-Density Lipoprotein Cholesterol and Risk of Ischemic Heart Disease | Cardiology | JAMA Internal Medicine | JAMA Network
Dr. Paul Mason – ‘Blood tests on a ketogenic diet – what your cholesterol results mean’ – YouTube
LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature: Expert Review of Clinical Pharmacology: Vol 11, No 10

תנגודת אינסולין

Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study

Fasting and the Fifty Percent Insulin Problem – Butter Makes Your Pants Fall Off
Metabolic syndrome and renal cell carcinoma
Identifying hyperinsulinaemia in the absence of impaired glucose tolerance: An examination of the Kraft database
Insulinoma induced hypoglycemia in a type 2 diabetic patient. – Abstract – Europe PMC
ד”ר רון רוזדייל – אינסולין: תפקידו הקריטי במחלות כרוניות. חלק א | בריאות בעברית
KRAFT Summary re-post: for those who missed it (cardiovascular disease explained) — The Fat Emperor
Insulin resistance as a predictor of age-related diseases. – PubMed – NCBI
Insulin Toxicity and How to Cure Type 2 Diabetes – YouTube
Detection of Diabetes Mellitus In Situ (Occult Diabetes) by Joseph Kraft, M
Insulin and Weight Gain – Hormonal Obesity
How We Get Fat | BodyRecomposition – The Home of Lyle McDonald
How do some cultures stay lean while still consuming high amounts of carbohydrates? « The Eating Academy | Peter Attia, M.D. The Eating Academy | Peter Attia, M.D.
Obesity. Cannot ignore insulin. It’s there to tell that fat where to go, and how to get there.
Effects of Acute Changes of Plasma Free Fatty Acids on Intramyocellular Fat Content and Insulin Resistance in Healthy Subjects
Kraft patterns in people with normal glucose tolerance | Lifestyle Before Medication
Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes | Diabetes Care
Insulin-sensitive obesity | Endocrinology and Metabolism
Hyperlipid: Musing about linoleic acid
Rolf Luft Award 2014, Prize Lecture by Professor Roger Unger – YouTube
Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes
Palmitate-induced Down-regulation of Sortilin and Impaired GLUT4 Trafficking in C2C12 Myotubes
Type of dietary fat and insulin resistance. – PubMed – NCBI
Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets
Differential Metabolic Effects of Saturated Versus Polyunsaturated Fats in Ketogenic Diets | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation.
Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance
Synergistic association of elevated serum free fatty acid and glucose levels with large arterial stiffness in a general population: The Nagahama Study – Metabolism – Clinical and Experimental
H2O2 Signalling Pathway: A Possible Bridge between Insulin Receptor and Mitochondria
Dr. Ted Naiman – ‘Insulin Resistance’ – YouTube
Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan: Cell Reports
Body fat distribution and peripheral insulin sensitivity in healthy men: role of insulin pulsatility | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes
Diabetes
Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling. – PubMed – NCBI
Homogeneous Insulin and C-Peptide Sensors for Rapid Assessment of Insulin and C-Peptide Secretion by the Islets
Association between fasting insulin and high-sensitivity C reactive protein in Korean adults | BMJ Open Sport & Exercise Medicine
Estimation and kinetic analysis of insulin-independent glucose uptake in human subjects. – PubMed – NCBI
Meta-Analysis and Dose-Response Metaregression: Circulating Insulin-Like Growth Factor I (IGF-I) and Mortality | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
The good and the bad in the link between insulin resistance and vascular calcification. – PubMed – NCBI
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome : Nature : Nature Research
Insulin: understanding its action in health and disease
IAS Distinguished Lecture : Prof Barbara Corkey (15 Apr 2016) – YouTube
Lower brain glucose levels found in people with obesity, type 2 diabetes | YaleNews
JCI – Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR).
Euglycaemic glucose clamp: what it can and cannot do, and how to do it – Heise – 2016 – Diabetes, Obesity and Metabolism – Wiley Online Library
JCI – Role of Insulin in Endogenous Hypertriglyceridemia
Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass | SpringerLink
BioVolt
Dr. Benjamin Bikman – ‘Insulin vs. Glucagon: The relevance of dietary protein’ – YouTube
Characteristics of hepatic insulin‐sensitive nonalcoholic fatty liver disease – Shigiyama – 2017 – Hepatology Communications – Wiley Online Library
Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease – Lomonaco – 2012 – Hepatology – Wiley Online Library
Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans | BMC Endocrine Disorders | Full Text
Insulin-sensitive obesity | American Journal of Physiology-Endocrinology and Metabolism
Long-term arsenic exposure and incidence of non-insulin-dependent diabetes mellitus: a cohort study in arseniasis-hyperendemic villages in Taiwan.
Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity | Clinical Chemistry
Why the carbohydrate-insulin model of obesity is probably wrong: A supplementary reply to Ebbeling and Ludwig’s JAMA article
TyG Index Calculator
Optimal cutoff for the evaluation of insulin resistance through triglyceride-glucose index: A cross-sectional study in a Venezuelan population – F1000Research
Hepatic insulin clearance is closely related to metabolic syndrome components. – PubMed – NCBI
Correlates of insulin clearance in apparently healthy non-obese Japanese men
Pulsatile Insulin Secretion Dictates Systemic Insulin Delivery by Regulating Hepatic Insulin Extraction In Humans | Diabetes
The impact of food order on postprandial glycemic excursions in prediabetes – Shukla – – Diabetes, Obesity and Metabolism – Wiley Online Library
Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. – PubMed – NCBI
Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete’s paradox – ScienceDirect
Insulin resistance indices and coronary risk in adults from Maracaibo city, Venezuela: A cross sectional study – F1000Research
Risks for All-Cause Mortality, Cardiovascular Disease, and Diabetes Associated With the Metabolic Syndrome | Diabetes Care
Effects of Diabetes and Level of Glycemia on All-Cause and Cardiovascular Mortality: The San Antonio Heart Study | Diabetes Care
Hypoglycemia and Risk of Cardiovascular Disease and All-Cause Mortality in Insulin-Treated People With Type 1 and Type 2 Diabetes: A Cohort Study | Diabetes Care
Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people – ScienceDirect
Insulin Resistance as a Predictor of Age-Related Diseases | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
The Risk of Offspring Psychiatric Disorders in the Setting of Maternal Obesity and Diabetes | Articles | Pediatrics
Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance: Dermato-Endocrinology: Vol 10, No 1
Mechanisms of Insulin Action and Insulin Resistance | Physiological Reviews
Maternal Obesity and Diabetes Linked to Autism in Children | The Scientist Magazine®
Inferring causal pathways among three or more variables from steady-state correlations in a homeostatic system
Hepatic and Extrahepatic Insulin Clearance Are Differentially Regulated: Results From a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data
One-Hour Postload Hyperglycemia: Implications for Prediction and Prevention of Type 2 Diabetes | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Intestinal glucose absorption is a key determinant of 1-hour post-load plasma glucose levels in non-diabetic subjects | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
One hour post-OGTT glucose improves the early prediction of type 2 diabetes by clinical and metabolic markers | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
High blood sugar during pregnancy ups risk of mother’s type 2 diabetes, child’s obesity | National Institutes of Health (NIH)
Dietary weight loss in insulin-resistant non-obese humans: Metabolic benefits and relationship to adipose cell size – Nutrition, Metabolism and Cardiovascular Diseases
Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis | SpringerLink
Diagnosing Insulin Resistance in the General Population | Diabetes Care
The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. – PubMed – NCBI
Black African men with early type 2 diabetes have similar muscle, liver and adipose tissue insulin sensitivity to white European men despite lower visceral fat | SpringerLink
Invited Review: Sodium-retaining effect of insulin in diabetes

סרטן

סרטן ותזונה קטוגנית

Thomas Seyfried: Cancer: A Metabolic Disease With Metabolic Solutions – YouTube
‫דיאטה קטוגנית כטיפול בסרטן (HD) – דר’ מרקולה מראיין את פרופסור תומס סיפריד (Thomas Seyfried)‬‎ – YouTube
Ketogenic diet beats chemotherapy for almost all cancers, says Thomas Seyfried – National Celebrity Fitness and Health | Examiner.com
The Glucose Ketone Index Calculator: A Simple Tool to Monitor Therapeutic Efficacy for Metabolic Management of Brain Cancer
Dominic D’Agostino and Fat Emperor talk Ketogenic Diets & Cancer – YouTube
Ketogenic Diets for Cancer. “What makes you think that ketone bodies will help?” | Richard David Feinman
Cancer as a metabolic disease: implications for novel therapeutics
Dominic D’Agostino (@DominicDAgosti2) | Twitter
Ketogenic Diets and Cancer: Emerging Evidence | Federal Practitioner
Cancer as a metabolic disease | Nutrition & Metabolism | Full Text
Cancer as a Metabolic Disease wtih Dr. Thomas Seyfried | Long Version – YouTube
Out of Warburg effect: An effective cancer treatment targeting the tumor specific metabolism and dysregulated pH.
Thomas Seyfried, PhD — Cancer as a Mitochondrial Metabolic Disease – YouTube
Points-Highlighted-by-Chad-Macias-2.pdf
Systematic review: isocaloric ketogenic dietary regimes for cancer patients | SpringerLink
Frontiers | Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy | Frontiers in Molecular Neuroscience
Need for new review of article on ketogenic dietary regimes for cancer patients
Ketogenic diet does not “beat chemo for almost all cancers” – Science-Based Medicine
Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2 | Cancer Cell International | Full Text
Is Cancer a Mitochondrial Disease? | Josh Mitteldorf
Elucidating the role of adipose tissue secreted factors in malignant transformation: Adipocyte: Vol 0, No ja
A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model
Regulation of brain insulin signaling: A new function for tau | JEM
Mitochondrial dysfunction and risk of cancer
Frontiers | Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up | Nutrition
AMA with Professor Thomas Seyfried! : ketoscience
omment on “Systematic Review: Isocaloric Ketogenic Dietary Regimes for Cancer Patients” by Erickson et al
WHO Says Meat Causes Cancer? by Georgia Ede, MD – YouTube
IJMS | Free Full-Text | Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet | HTML
Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease? (EP.30) – Peter Attia

בלוגים ואתרים

Fat Head » About the Film

myzerocarblife.jamesdhogan.com/wp/
Intensive Dietary Management Blog
Empirica
The Carb-Sane Asylum
Low Carb USA
Free The Animal
חי בריא
The Fat Emperor
The Eating Academy | Peter Attia, M.D. The Eating Academy | Peter Attia, M.D.
Hyperlipid
KetoNutrition: Practical Information on Ketogenic Diets and Metabolic Therapies
George Henderson – Google+
Lifestyle Before Medication | A pharmacist’s perspective on health and metabolic disease
Authority Nutrition – Daily Articles About Nutrition and Health
The High-fat Hep C Diet
Ketogenic Forums
Raw Food SOS | Rescuing good health from bad science.
Tuit Nutrition
optimising nutrition | nutritious ideas for diabetics (and the rest of us)
Chris Kresser – Paleo
Nige’s Diet & Nutrition Blog
Wildly Fluctuating
The Ketogenic Diet for Health
Tucker Goodrich| Twitter
BreakNutrition – Beyond nutrition myths
Richard David Feinman | Richard Feinman, the Other
Low Carb High Fat Diet Experts
The poor, misunderstood calorie | calories proper
Yelling Stop
keto reddit
The High-fat Hep C Diet
Don’t Eat That – The food pyramid is a lie, fat is good for you, and many (if not most) health problems are treatable with diet alone. I’m in remission from severe arthritis (multiple joints replaced), chronic fatigue, depression and a plethora of other s
Human Performance Outliers Podcast
Podcast – Peter Attia
Peak Human Podcast | Optimum Health | by Food Lies
The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Blog – Intensive Dietary Management (IDM)
Virta Health Blog – Blog | Virta Health
Diet Doctor – Making Low Carb and Keto Simple
Heretic
Tuit Nutrition – YouTube
Burn Fat Not Sugar
Fat Fueled Family

מחקרים

Hall study

Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents
Comparison of a carbohydrate-free diet vs. fasting on plasma glucose, insulin and glucagon in type 2 diabetes
Short-term effects of ketogenic diet on anthropometric parameters, body fat distribution, and inflammatory cytokine production in GLUT1 deficiency syndrome
Comparison of a carbohydrate-free diet vs. fasting on plasma glucose, insulin and glucagon in type 2 diabetes – Metabolism – Clinical and Experimental
Glucose uptake by the brain on chronic high-protein weight-loss diets with either moderate or low amounts of carbohydrate
23 Studies on Low-Carb and Low-Fat Diets – Time to Retire The Fad | Health For Everyone
23 Studies on Low-Carb and Low-Fat Diets – Time to Retire The Fad
Top 13 Nutrition Lies That Made The World Sick and Fat
PLOS ONE: Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome
The 11 Most Destructive Nutrition Lies Ever Told – Business Insider
Small Amounts of Gluten in Subjects With Suspected Nonceliac Gluten Sensitivity: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial – Clinical Gastroenterology and Hepatology
Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease
Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man | SpringerLink
Assessment of insulin sensitivity/resistance
The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: A pilot study
Evidence that supports the prescription of low-carbohydrate high-fat diets: a narrative review
Dose-Response Effect of Elevated Plasma Free Fatty Acid on Insulin Signaling
Association of Type 2 Diabetes with Submicron Titanium Dioxide Crystals in the Pancreas – Chemical Research in Toxicology (ACS Publications)

Taubes

Catching up on lost time – the Ancestral Health Symposium, food reward, palatability, insulin signaling and carbohydrates, kettles, pots and other odds and ends (with some philosophy of science as a special added attraction). Part I.

Catching up on lost time – the Ancestral Health Symposium, food reward, palatability, insulin signaling and carbohydrates… Part II(a)
Catching up on lost time – the Ancestral Health Symposium, food reward, palatability, insulin signaling and carbohydrates… Part II(b)
Catching up on lost time – the Ancestral Health Symposium, food reward, palatability, insulin signaling and carbohydrates… Part II(c)
Catching up on lost time – the Ancestral Health Symposium, food reward, palatability, insulin signaling and carbohydrates… Part II(d)

צידיים-לקטים

Woolly mammoth diet mystery solved by DNA analysis – Technology & Science – CBC News

BBC Nature – Ice age videos, news and facts
Longevity Among Hunter-Gatherers: A Cross-Cultural Examination
Barry Groves: Homo Carnivorus What We Are Designed to Eat – YouTube
Hunter-Gatherer Macronutrient Ratios: More Data – Perfect Health Diet | Perfect Health Diet
Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets
Origins of Genus Homo–Southern Africa and Origin of Homo; Adaptive Shifts; Energetics and Ecology – YouTube
Hunter-Gatherer Energetics and Human Obesity
Unprecedented wave of large-mammal extinctions linked to ancient humans | Nebraska Today | University of Nebraska–Lincoln
Unprecedented wave of large-mammal extinctions linked to ancient humans | Nebraska Today | University of Nebraska–Lincoln
Myths about Paleo carbs – Part 2 – – BreakNutrition
Myths about Paleo carbs – Part 2 – – BreakNutrition
Redefining Metabolic Syndrome as a Fat Storage Condition Based on Studies of Comparative Physiology
Redefining Metabolic Syndrome as a Fat Storage Condition Based on Studies of Comparative Physiology
Impact of Carnivory on Human Development and Evolution Revealed by a New Unifying Model of Weaning in Mammals
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European | Nature
plants – zerocarb

ויטמנים ותוספים

D is for Debacle – The Crucial Story of Vitamin D and Human Health – YouTube

Vitamin A Under Attack Down Under | Primal Body Primal Mind
Phil Maffetone – Vitamin A and the Beta-Carotene Myth
The Calcium Story
10 Reasons Why Fructose Is Bad | Paleo Leap
Fructose, Bayes’s Theorem, Hill’s criteria and Murphy’s Law — Richard Feinman, Ph.D. (AHS14) – YouTube
5 Reasons High Fructose Corn Syrup Will Kill You – Dr. Mark Hyman
כמה אומגה 3 צריך ביום?
Natural Toxins in Food
Plants Bite Back – Weston A Price
Protein and its Effect on Bones- Asgard Fit
פליאו דיאט Paleo Diet IL | הרבה יותר משרציתם לדעת על אנטי נוטריאנטים – חלק א’
Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. – PubMed – NCBI
Ketogenic diet and Vitamin C: the 101 – BreakNutrition
Cutaneous malignant melanoma incidences analyzed worldwide by sex, age, and skin type over personal Ultraviolet-B dose shows no role for sunburn but implies one for Vitamin D3

Ultra low fat

Thoughts on the Pritikin Diet

Thoughts on the Kempner Rice Diet – Intensive Dietary Management
sci-hub.cc/10.1001/archinte.1975.00330120053008
jn.nutrition.org.sci-hub.cc/content/16/6/511.full.pdf
jphysiol01610-0047.pdf
care.diabetesjournals.org.sci-hub.cc/content/6/3/268.short
Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise. – PubMed – NCBI
ajcn.nutrition.org.sci-hub.cc/content/29/8/895.full.pdf
www.sciencedirect.com.sci-hub.cc/science/article/pii/0002914992909814
In Defense of Low Fat: A Call for Some Evolution of Thought (Part 1) | Denise Minger
A low-carbohydrate/high-fat diet improves glucoregulation in type 2 diabetes mellitus by reducing postabsorptive glycogenolysis. – PubMed – NCBI
In Defense of Low Fat: A Call for Some Evolution of Thought (Part 1) | Denise Minger

מיטוכונדריה

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling… – PubMed – NCBI
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatt… – PubMed – NCBI
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. – PubMed – NCBI
Science-2005-Lowell-384-7-OX-phos-Fa-metabol-T2d.pdf
Diabetes
Mitochondria and Diabetes: Genetic, Biochemical, and Clinical Implications of the Cellular Energy Circuit
Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency. – PubMed – NCBI
Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage
Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer
Mitochondrial uncoupling proteins and energy metabolism
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
Being right on Q: shaping eukaryotic evolution
Modulation of oxidative stress and mitochondrial function by the ketogenic diet
The ketogenic diet increases mitochondrial uncoupling protein levels and activity. – PubMed – NCBI
DNP
Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease
Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species
Redox Control of Mitochondrial Calcium Uptake
Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise tr… – PubMed – NCBI
Skeletal muscle insulin resistance: role of mitochondria and other ROS sources
Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria | Heart and Circulatory Physiology
Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadi… – PubMed – NCBI
Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice – Das – 2017 – Journal of Pineal Research – Wiley Online Library
Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in … – PubMed – NCBI
Adiponectin partially rescues high glucose/high fat-induced impairment of mitochondrial biogenesis and function in a PGC-1α dependent manner
Mitophagy in neurodegeneration and aging
Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity
The role of mitochondria in cardiac development and protection. – PubMed – NCBI
Mitochondrial metabolism and energy sensing in tumor progression
Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo
Mitochondrial Uncoupling Proteins – Facts and Fantasies
Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity
BioEssays – – Wiley Online Library
Mitochondrial uncoupling proteins regulate angiotensin-converting enzyme expression: crosstalk between cellular and endocrine metabolic regulators suggested by RNA interference and genetic studies – Dhamrait – 2016 – BioEssays – Wiley Online Library
Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it – Speijer – 2010 – BioEssays – Wiley Online Library
Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it
Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control
Role of Mitochondrial Dysfunction in Insulin Resistance | Circulation Research
Reconsidering ideas regarding the evolution of peroxisomes: the case for a mitochondrial connection | SpringerLink
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency: Cell Reports
Role of Mitochondrial Dysfunction in Hypertension and Obesity | SpringerLink
Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal – Mills – 2016 – European Journal of Immunology – Wiley Online Library
Mitochondrial DNA in innate immune responses and inflammatory pathology : Nature Reviews Immunology : Nature Research
Advances in Immunology – Google ספרים
NIH discovery in mice could lead to new class of medications to fight mid-life obesity – NHLBI, NIH
https://l.facebook.com/l.php?u=http%3A%2F%2Fsci-hub.cc%2Fsaveme%2Ffb68%2F10.1016%40j.cmet.2017.04.008.pdf&h=ATNUXYp3kQs5HoGYwlCYMSkGW6p8Hk9I6lv3LU5Y9MI54YJtufUBMoYKFB4AmPf8uey2DHRI1E53AqLQtMPSzkpD6pY-_0m200TZJ6gEgsdP3Lw2X3wCSwnGhEC9AeQ1a6A
Mitochondrial Calcium Signaling and Energy Metabolism
<H3″>NAD/NADH+
The Redox State of Free Nicotinamide-Adenine Dinucleotide in the Cytoplasm and Mitochondria of Rat Liver
The Determination of the Redox States and Phosphorylation Potentialin Living Tissues and Their Relationship to Metabolic Control ofDisease Phenotypes
Insulin, ketone bodies, and mitochondrial energy transduction
Metabolic Master Regulators: Sharing Information among Multiple Systems

 

Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione. – PubMed – NCBI
Fatty Acids in Energy Metabolism of the Central Nervous System
The Neuromediator Glutamate, through Specific Substrate Interactions, Enhances Mitochondrial ATP Production and Reactive Oxygen Species Generation in Nonsynaptic Brain Mitochondria
Mitochondrial control of immunity: beyond ATP : Nature Reviews Immunology : Nature Research
Modeling of Mitochondria Bioenergetics Using a Composable Chemiosmotic Energy Transduction Rate Law: Theory and Experimental Validation
Mitochondrial Pathways and Respiratory Control
Chapter One – Macrophages and Mitochondria: A Critical Interplay Between Metabolism, Signaling, and the Functional Activity
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages: Cell
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency: Cell Reports
Mitochondrial physiology in health and disease: Biogenesis, growth and function, Fleming Dela – YouTube
AHS12 Chris Masterjohn — Oxidative Stress & Carbohydrate Intolerance: An Ancestral Perspective – YouTube
Acute exercise alters skeletal muscle mitochondrial respiration and H2O2 emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men
Acute exercise alters skeletal muscle mitochondrial respiration and H2O2 emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men
Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus
Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus
Relationship Between Testosterone Levels, Insulin Sensitivity, and Mitochondrial Function in Men | Diabetes Care
Relationship Between Testosterone Levels, Insulin Sensitivity, and Mitochondrial Function in Men | Diabetes Care
Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders
Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload
Mitochondrial dysfunction-related lipid changes occur in non-alcoholic fatty liver disease progression
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance: Cell Metabolism

שומן

Viewpoints on the Way to the Consensus Session

Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. – PubMed – NCBI
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
Elevation of Free Fatty Acids Induces Inflammation and Impairs Vascular Reactivity in Healthy Subjects
Increased oxidative stress in obesity and its impact on metabolic syndrome
Adiponectin profile and Irisin expression in Italian obese children: Association with insulin-resistance. – PubMed – NCBI
Mechanisms for the anti-obesity actions of bofutsushosan in high-fat diet-fed obese mice
Adipose tissue remodeling in rats exhibiting fructose-induced obesity | SpringerLink
Nutrients | Free Full-Text | Long-Term Fructose Intake Increases Adipogenic Potential: Evidence of Direct Effects of Fructose on Adipocyte Precursor Cells | HTML
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Macrophages, Immunity, and Metabolic Disease
Obesity is associated with macrophage accumulation in adipose tissue
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
JCI – Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice
Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights | SpringerLink
Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization
Adipocyte size as a determinant of metabolic disease and adipose tissuedysfunction.pdf
Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses. – PubMed – NCBI
Succinate: a metabolic signal in inflammation: Trends in Cell Biology
Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid–Induced Macrophage Cell Death through Enhancing Ceramide Production | The Journal of Immunology
Advances in Immunology – Google ספרים
Different Adipose Depots: Their Role in the Development of Metabolic Syndrome and Mitochondrial Response to Hypolipidemic Agents
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes | SpringerLink
Calories-in-calories-out, substrate cycles and diesel engines | Richard David Feinman
Adipokines, diabetes and atherosclerosis: an inflammatory association
Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
Lipolysis, Fat Mobilization, Fatty Acid (beta, alpha, omega) Oxidation, Ketogenesis
Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis : Nature Cell Biology : Nature Research
Visceral fat and metabolic inflammation: the portal theory revisited – Item – 2012 – Obesity Reviews – Wiley Online Library
Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance | Scientific Reports
Pathophysiology of Human Visceral Obesity: An Update
Obesity | Nature Reviews Disease Primers
Adipose Tissue, Inflammation (Meta-inflammation) and Obesity Management (PDF Download Available)
Adapting to obesity with adipose tissue inflammation : Nature Reviews Endocrinology : Nature Research
Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity: Cell
Molecular mechanisms underlying metabolic syndrome: the expanding role of the adipocyte
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation: Cell Metabolism
Sex differences in fat storage, fat metabolism, and the health risks from obesity: possible evolutionary origins | British Journal of Nutrition | Cambridge Core
Dietary balance during pregnancy is associated with fetal adiposity and fat distribution
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota: Cell Metabolism
Adiponectin Resistance and Proinflammatory Changes in the Visceral Adipose Tissue Induced by Fructose Consumption via Ketohexokinase-Dependent Pathway
Metabolic fate of fructose in human adipocytes: a targeted 13C tracer fate association study
Macrophage recruitment in obese adipose tissue
Losing a single gram of fat can reverse diabetes? – T2D 9 – Intensive Dietary Management
Nutrients | Free Full-Text | Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome | HTML
Adipose tissue remodeling and obesity
The ominous triad of adipose tissue dysfunction: Inflammation, fibrosis, and impaired angiogenesis (PDF Download Available)
Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis | Springer for Research & Development
Adiponectin, the past two decades | Journal of Molecular Cell Biology | Oxford Academic
Lipodystrophy and obesity are associated with decreased number of T cells with regulatory function and pro-inflammatory macrophage phenotype. – PubMed – NCBI
Adipose Cell Size and Regional Fat Deposition as Predictors of MetabolicResponse to Overfeeding in InsulinResistant and Insulin-Sensitive Humans
Fitness, adiposopathy, and adiposity are independent predictors of insulin sensitivity in middle-aged men without diabetes | SpringerLink
Comparison between body mass index and a body shape index with adiponectin/leptin ratio and markers of glucose metabolism among adolescents: Annals of Human Biology: Vol 44, No 6
Adiponectin-leptin ratio: a promising index to estimate adipose tissue dysfunction. Relation with obesity-associated cardiometabolic risk: Adipocyte: Vol 0, No ja
Inter-relationships of the chronobiotic, melatonin, with leptin and adiponectin: implications for obesity – Szewczyk-Golec – 2015 – Journal of Pineal Research – Wiley Online Library
Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation
Fructose-induced Inflammation and Increased Cortisol: A New Mechanism for How Sugar Induces Visceral Adiposity – Progress in Cardiovascular Diseases
Insulin Inhibits IL-10–Mediated Regulatory T Cell Function: Implications for Obesity | The Journal of Immunology
העקרון הקרניבורי
Causes and mechanisms of adipocyte enlargement and adipose expansion – Haczeyni – 2017 – Obesity Reviews – Wiley Online Library
4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance – ScienceDirect
TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue | Nature Communications
Dysregulated lipid storage and its relationship with insulin resistance and cardiovascular risk factors in non-obese Asian patients with type 2 diabetes: Adipocyte: Vol 0, No ja
Insulin resistance in lean and overweight non-diabetic Caucasian adults: Study of its relationship with liver triglyceride content, waist circumference and BMI
Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production: Cell Metabolism
Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
Adipose tissue and adipocyte dysregulation. – PubMed – NCBI
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans | NEJM
Adipose tissue and adipocyte dysregulation. – PubMed – NCBI
Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance | Nature
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans | NEJM
Dynamics of human adipose lipid turnover in health and metabolic disease | Nature
JCI – Insulin resistance causes inflammation in adipose tissue
Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway | Diabetes
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus | International Journal of Obesity
Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis
Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation | Clinical Science
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans: Cell Metabolism
Genetic Predisposition for Type 2 Diabetes, but Not for Overweight/Obesity, Is Associated with a Restricted Adipogenesis
Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Exendin-4 Upregulates Adiponectin Level in Adipocytes via Sirt1/Foxo-1 Signaling Pathway
miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity | Diabetes
Do adipose tissue macrophages promote insulin resistance or adipose tissue remodelling in humans? – PubMed – NCBI
Impact of Age on the Relationships of Brown Adipose Tissue With Sex and Adiposity in Humans
Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance – ScienceDirect
Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification
Subcutaneous Adipose Tissue Accumulation Protects Systemic Glucose Tolerance and Muscle Metabolism: Adipocyte: Vol 0, No ja
Adipose Overexpression of Phosphoenolpyruvate Carboxykinase Leads to High Susceptibility to Diet-Induced Insulin Resistance and Obesity | Diabetes
Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis: Cell Metabolism
Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse | SpringerLink
Infographic: The Omentum’s Role in Health and Disease | The Scientist Magazine®
Belly Fat Has a Role to Play in Fighting Infections | The Scientist Magazine®
Mesenteric fat—control site for bacterial translocation in colitis? | Mucosal Immunology
Indirect Regulation of Endogenous Glucose Production by Insulin: The Single Gateway Hypothesis Revisited | Diabetes
Adipose Tissue, Inter-Organ Communication, and the Path to Type 2 Diabetes: The 2016 Banting Medal for Scientific Achievement Lecture | Diabetes
Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production: Immunity
The many secret lives of adipocytes: implications for diabetes | SpringerLink
Mechanisms of weight regain after weight loss — the role of adipose tissue | Nature Reviews Endocrinology
Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity. – PubMed – NCBI
Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity | Physiological Reviews
The Health Risks of Obesity Have Been Exaggerated

בלוטת התריס

Thyroid hormones and mitochondria: With a brief look at derivatives and analogues

Molecular regulation of thyroid gland function. – PubMed – NCBI
Introducing the Thyroid Gland as Another Victim of the Insulin Resistance Syndrome
The Ketogenic Diet for Health: The Effect of Ketogenic Diets on Thyroid Hormones
Tuit Nutrition: Let’s Talk About Thyroid — Intro: Thyroid Function & Testing (Pt. 1/3)
Yelling Stop: Thyroid and Low-Carb: What Do Thyroid Hormones Do?
Does Your Thyroid Need Dietary Carbohydrates? – Blog | Virta Health
Thyroid hormones are positively associated with insulin resistance early in the development of type 2 diabetes | SpringerLink
Thyroid Disorders and Diabetes Mellitus
Effect of thyroid hormones on oxidative and nonoxidative glucose metabolism in humans | American Journal of Physiology-Endocrinology and Metabolism
Introducing the Thyroid Gland as Another Victim of the Insulin Resistance Syndrome | Thyroid
The Role of Insulin Resistance/Hyperinsulinism on the Rising Trend of Thyroid and Adrenal Nodular Disease in the Current Environment
Why Can Insulin Resistance Be a Natural Consequence of Thyroid Dysfunction?

Metformin

Activation of the AMP-activated Protein Kinase by the Anti-diabetic Drug Metformin in Vivo

Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner
Stop the Metformin Madness- Hormones Matter
Repurposing metformin: an old drug with new tricks in its binding pockets

פיזיולוגיה כללי

Gluconeogenesis – BreakNutrition

Role of Free Oxaloacetate in Ketogenesis – SIESS – 1982 – The FEBS Journal – Wiley Online Library
Episode 24 – Tucker and Gabor on Seed Oils vs Refined Carbs – Part 2 – BreakNutrition
Regulation of hepatic glucose metabolism in health and disease : Nature Reviews Endocrinology : Nature Research
Access : AMPK: a nutrient and energy sensor that maintains energy homeostasis : Nature Reviews Molecular Cell Biology
Whole-Body Glycolysis Measured by the Deuterated-Glucose Disposal Test Correlates Highly With Insulin Resistance In Vivo | Diabetes Care
Malonyl-CoA, a key signaling molecule in mammalian cells. – PubMed – NCBI
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation: Cell Metabolism
Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I.
Aging | Fat accumulation in <i>Caenorhabditis elegans</i> triggeredby the electrophilic lipid peroxidation product 4-Hydroxynonenal (4-HNE) – Full Text
Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP | Nature Communications
Effect of intermittent fasting and refeeding on insulin action in healthy men
mTOR Signaling in Growth, Metabolism, and Disease: Cell
Metabolic Instruction of Immunity: Cell
Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis: Molecular Cell
Quantitative Physiology of Human Starvation: Adaptations of Energy Expenditure, Macronutrient Metabolism and Body Composition – Springer
The respiratory chain
Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin | Heart and Circulatory Physiology
Triglyceride Fatty Acid Cycle.pdf
A Model of the Kinetics of Insulin in Man
Influence of medium-chain and long-chain triacylglycerols on the control of food intake in men. – PubMed – NCBI
Randomized control trial assessing impact of increased sunlight exposure versus Vitamin D supplementation on lipid profile in Indian Vitamin D deficient men Patwardhan VG, Mughal ZM, Padidela R, Chiplonkar SA, Khadilkar VV, Khadilkar AV – Indian J Endocr
Marshall D. McCue (auth.), Marshall D. McCue (eds.)-Comparative Physiology of Fasting, Starvation, and Food Limitation-Springer-Verlag Berlin Heidelberg (2012).pdf
Triacylglycerol metabolism
Multiple Factors Related to the Secretion of Glucagon-Like Peptide-1
Leptin therapy, insulin sensitivity, and glucose homeostasis
The Carb-Sane Asylum: What Does Insulin Regulate Anyway?
A Closer Look at Cortisol
Rolf Luft Award 2014, Prize Lecture by Professor Roger Unger – YouTube
Metabolic signalling
AMP-activated protein kinase (AMPK) beyond metabolism
AMPK: positive and negative regulation, and its role in whole-body energy homeostasis – ScienceDirect
Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?
AMPK at the Nexus of Energetics and Aging
Serum leptin levels in women with anorexia nervosa | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Rhythmic Leptin Is Required for Weight Gain from Circadian Desynchronized Feeding in the Mouse
Protein, fat, and carbohydrate requirements during starvation: anaplerosis and cataplerosis.
Metabolic Flexibility in Health and Disease: Cell Metabolism
Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance
Why does brain metabolism not favor burning of fatty acids to provide energy? – Reflections on disadvantages of the use of free fatty acids as fuel for brain
The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids: Cell Metabolism
Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage | Cell Research
Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation: Cell
FULL TEXT – Crohn’s disease successfully treated with the paleolithic ketogenic diet – International Journal of Case Reports and Images (IJCRI)
The Big Vitamin D Mistake
Great News! AntidepressantsWork-Or Not – The CARB Syndrome Project
The Big Vitamin D Mistake
The Homeostatic Force of Ghrelin: Cell Metabolism
High Glycemic Index Metabolic Damage – a Pivotal Role of GIP and GLP-1: Trends in Endocrinology & Metabolism
Effect of diet composition on metabolic adaptations to hypocaloric nutrition: comparison of high carbohydrate and high fat isocaloric diets | The American Journal of Clinical Nutrition | Oxford Academic
Prolonged saturated fat–induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a novel feature of fatty liver | The Am
Fatty acids stimulate insulin secretion from human pancreatic islets at fasting glucose concentrations via mitochondria-dependent and -independent mechanisms

oxaloacetate

 

ctivation of AMP-protein activated kinase by oxaloacetate compounds
Studies on Anti-diabetic Effect of Sodium Oxaleacetate
Tolerability and pharmacokinetics of oxaloacetate 100 mg capsules in Alzheimer’s subjects – ScienceDirect
Oxaloacetate: The Next Big Brain & Anti-Aging Supplement? | The Quantified Body
Oxaloacetate – Scientific Review on Usage, Dosage, Side Effects | Examine.com

 

mice obese diet
Fatty acids stimulate insulin secretion from human pancreatic islets at fasting glucose concentrations via mitochondria-dependent and -independent mechanisms
Human Performance Outliers Podcast: Episode 13: Dr. Ben Bikman
mice obese diet
Reversal of Hypertriglyceridemia, Fatty Liver Disease and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
One of the most important ingredients in breast milk you’ve never heard of
Human Performance Outliers Podcast: Episode 13: Dr. Ben Bikman
Relatively high-protein or ‘low-carb’ energy-restricted diets for body weight loss and body weight maintenance? – PubMed – NCBI
One of the most important ingredients in breast milk you’ve never heard of
AMPK – a nutrient and energy sensor that maintains energy homeostasis
Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward: Cell Metabolism
Omega-6 fatty acids: the alternative hypothesis for diseases of civilization – BreakNutrition
Gluconeogenesis and the Cori cycle in 12-, 20-, and 40-h-fasted humans | American Journal of Physiology-Endocrinology and Metabolism
Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating
Effects of isoenergetic overfeeding of either carbohydrate or fat in young men | British Journal of Nutrition | Cambridge Core
The Carbohydrate-Insulin Model of Obesity: Beyond “Calories In, Calories Out” | JAMA Internal Medicine | JAMA Network
Monounsaturated Fat–Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects | Diabetes Care
Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron | The American Journal of Clinical Nutrition | Oxford Academic
Review on iron and its importance for human health
Dietary Fat, but Not Protein or Carbohydrate, Regulates Energy Intake and Causes Adiposity in Mice: Cell Metabolism
7 Longevity Biomarkers to Track | Mark’s Daily Apple
Linoleic acid and the pathogenesis of obesity – ScienceDirect
Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance | International Journal of Obesity
Metabolic Effects of Long-Term Reduction in Free Fatty Acids With Acipimox in Obesity: A Randomized Trial | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Is leptin resistance the cause or the consequence of diet-induced obesity? | International Journal of Obesity
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
Role of Pyruvate Dehydrogenase Kinase 4 in Regulation of Blood Glucose Levels
Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease
Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward: Cell Metabolism
Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial | The BMJ
Obesity Energetics: Body Weight Regulation and the Effects of Diet Composition
A review on gastric leptin: the exocrine secretion of a gastric hormone
Frontiers | Hallmarks of Aging: An Autophagic Perspective | Endocrinology

שמנים בתזונה

Good Lard, Bad Lard: What Do You Get When You Cross a Pig and a Coconut? – The Weston A. Price Foundation

Limited Effect of Dietary Saturated Fat on Plasma Saturated Fat in the Context of a Low Carbohydrate Diet
Why Soy Is Unsustainable And Beef Is Better For The Planet – Blog | Super Human Radio
Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar.
Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet
Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. – PubMed – NCBI
Episode 24 – Tucker and Gabor on Seed Oils vs Refined Carbs – Part 2 – BreakNutrition
Reactive aldehydes – second messengers of free radicals in diabetes mellitus: Free Radical Research: Vol 47, No sup1
Omega-6 vegetable oils as a driver of coronary heart disease: the oxidized linoleic acid hypothesis | Open Heart
The High-fat Hep C Diet: A Grand Unified Theory of Polyunsaturated Fatty Acid Misbehaviour in Inflammatory Disease
Effect of a 6-Month Intervention with Cooking Oils Containing a High Concentration of Monounsaturated Fatty Acids (Olive and Canola Oils) Compared with Control Oil in Male Asian Indians with Nonalcoholic Fatty Liver Disease | Diabetes Technology & Therapeutics
Hyperlipid: On drinking varnish
Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century
Joe Health Blog: Vegetable Oils are Bad: Tucker Goodrich, Peak Human listening companion (Part 3)
Diet and disease–the Israeli paradox: possible dangers of a high omega-6 polyunsaturated fatty acid diet
Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA | American Journal of Physiology-Heart and Circulatory Physiology
Yelling Stop: What’s Worse—Carbs or Seed Oils? Understanding a High-PUFA Diet.
Dietary fatty acids — The n-6n-3 balance and chronic elderly diseases. Excess linoleic acid and relative n-3 deficiency syndrome seen in Japan – ScienceDirect
Omega-6 fatty acids: the alternative hypothesis for diseases of civilization – BreakNutrition
Requirement of Essential Fatty Acid for Mammary Tumorigenesis in the Rat | Cancer Research
Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half Century
Migration Patterns and Breast Cancer Risk in Asian-American Women | JNCI: Journal of the National Cancer Institute | Oxford Academic
Association between cooking oil fume exposure and lung cancer among Chinese nonsmoking women: a meta-analysis
Exploring the Impact of n-6 PUFA-rich Oilseed Production on Commercial Butter Compositions Worldwide – Journal of Agricultural and Food Chemistry (ACS Publications)
Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans – ScienceDirect

כללי

databases

NIH Data Sharing Repositories
Waist-to-height ratio more accurate than BMI in identifying obesity, new study shows — ScienceDaily
Subclinical Diabetes
Channel 4 News – This state school in England teaches kids how to…
Whole Health Source: The Carbohydrate Hypothesis of Obesity: a Critical Examination
Four Things Your Doctor Didn’t Tell You About High Blood Pressure! – YouTube
The China Study: Fact or Fallacy? | Raw Food SOS
Can Humans Digest Meat? | Roar of Wolverine
Leading Causes Of Death In 1900 And Today – Business Insider
Science For Smart People – YouTube
The McGovern Report – YouTube
Academic studies questioning current dietary advice – Zoë Harcombe
Whole Health Source: More Thoughts on the Recent Low-fat vs. Low-carb Metabolic Ward Study
low fat
AHS12 Georgia Ede MD Little Shop of Horrors? The Risks and Benefits of Eating Plants – YouTube
4 Reasons Why Some People Do Well as Vegans (While Others Fail)
Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity
An investigation of the false discovery rate and the misinterpretation of p-values | Open Science
Your Brain on Plants: The Ultimate Guide to Micronutrients and Mental Health – Diagnosis:Diet
The Pitfalls of Body Fat “Measurement”, Part 6: Dual-Energy X-Ray Absorptiometry (DEXA) – Weightology
Comparison of means calculator
The crown joules: energetics, ecology, and evolution in humans and other primates – Pontzer – 2017 – Evolutionary Anthropology: Issues, News, and Reviews – Wiley Online Library
Dynamic status of metabolically healthy overweight/obesity and metabolically unhealthy and normal weight and the risk of type 2 diabetes mellitus: A cohort study of a rural adult Chinese population – Obesity Research & Clinical Practice
סיבים
“Vitamin C from the evolutionary perspective” by Zsófia Clemens and Csaba Tóth
Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c – ScienceDirect
ההוכחה הכי פשוטה שבשר ושומן מן החי לא אחראים למחלות הציוויליזציה | פליאו סטייל
The hierarchy of disagreement: The best and worst argument techniques | Big Think
WPHNA World Public Health Nutrition Association
Court rules in favor of USDA in COOL case
Dietary Intake—How Do We Measure What People Are Really Eating? – Johnson – 2002 – Obesity Research – Wiley Online Library

מעי

Insulin and glycemic responses in healthy humans to native starches processed in different ways: correlation with in vitro alpha-amylase hydrolysis | The American Journal of Clinical Nutrition | Oxford Academic

Episode 7 – How processed starches affect metabolic responses – BreakNutrition
Incretin and islet hormonal responses to fat and protein ingestion in healthy men | American Journal of Physiology-Endocrinology and Metabolism
Episode 8 – starch digestibility and limitations of the glycemic response – BreakNutrition
(2) Gabor Erdosi: Part 2 of 2 – Insulin, Incretins – and the Perils of Processed Food Carbs – YouTube
SGLT2 inhibitors and GLP-1 receptor agonists: a sound combination – The Lancet Diabetes & Endocrinology
Glucagon-Like Peptide 1 Interacts with Ghrelin and Leptin to Regulate Glucose Metabolism and Food Intake through Vagal Afferent Neuron Signaling | The Journal of Nutrition | Oxford Academic
A high carbohydrate, but not fat or protein meal attenuates postprandial ghrelin, PYY and GLP-1 responses in Chinese men
Glucose-Dependent Insulinotropic Polypeptide | Diabetes
Diet: Friend or Foe of Enteroendocrine Cells: How It Interacts with Enteroendocrine Cells | Advances in Nutrition | Oxford Academic
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet | American Journal of Physiology-Endocrinology and Metabolism
FoodNews2018 gerdosi.pdf – Google Drive
FN2018_RefList.pdf – Google Drive
Gabor Erdosi Talk at FoodNews Conference Prague – Processed Food Perils! – YouTube
Incretin hormones: Their role in health and disease – Nauck – 2018 – Diabetes, Obesity and Metabolism – Wiley Online Library
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? – PubMed – NCBI
https://optimisingnutrition.com/2018/06/23/dont-eat-for-winter/
Dr. Paul Mason – ‘From fibre to the microbiome: low carb gut health’ – YouTube
Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine | Endocrinology | Oxford Academic
Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects | The American Journal of Clinical Nutrition | Oxford Academic
Effect of chicken, fat and vegetable on glycaemia and insulinaemia to a white rice-based meal in healthy adults. – PubMed – NCBI
Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism | Molecular Psychiatry
Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models | Science Translational Medicine
Particle size distribution of brown and white rice during gastric digestion measured by image analysis. – PubMed – NCBI
FFF24 – Fahad Ahmad — Fat Fueled Family

גלוטמין

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport

Glutamine and cancer: cell biology, physiology, and clinical opportunities
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
Role of Glutamate Dehydrogenase in Cancer Growth and Homeostasis | IntechOpen

רעב ושובע

Home – PubMed – NCBI

Sci-Hub: removing barriers in the way of science

 

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